Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

Blog Article

1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity associated with bortezomib, a proteasome inhibitor used in the treatment of numerous myeloma. Its synthesis or study is very important for guaranteeing the purity and security of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor during the synthesis of abiraterone acetate, a drug Utilized in the treatment of prostate most cancers by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-ten-1): A key compound from the synthesis of imatinib, a drug that targets particular forms of most cancers, such as Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats several cancers including breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are generally intermediates in the synthesis of gemcitabine, an anti-cancer drug. Their analyze is significant for optimizing the manufacturing course of action and ensuring substantial purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is employed to take care of breast most cancers, and these intermediates are involved in its creation.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist used in the treatment method of breast cancer. Several intermediates assist in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug helpful in treating cancers including 3 ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Utilized in the procedure of colorectal most cancers and little cell lung cancer.
3-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is involved with the synthesis of adamantane derivatives, which have a variety of purposes, together with antiviral Homes.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for form two diabetes that inhibits the enzyme DPP-four to regulate blood sugar ranges.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is CAS NO. 848133-35-7 linked to the synthesis of assorted gluconic acid derivatives, which happen to be Utilized in food stuff, pharmaceutical, and industrial applications.
Canagliflozin Intermediate two: A precursor during the synthesis of canagliflozin, a medication made use of to deal with form two diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).